Diphtheria Immunization with Fluid Toxoid and Alum-Precipitated Toxoid
نویسندگان
چکیده
منابع مشابه
Studies on Tetanus Toxoid: III. Antitoxic Response in Guinea Pigs Immunized with Tetanus Alum-precipitated Toxoid Followed by Tetanus Spores.
When an individual has been given one or more injections of tetanus toxoid and, at a later date, is injured and possibly infected with Clostridium tetani, what further precautions should be taken: (1) Administer antitoxin? (2) Give another injection of tetanus toxoid to accelerate the production of antitoxin? (3) Give no further treatment, depending on his present immunity to take care of the i...
متن کاملImmunization with Tetanus Toxoid
Although immunization with tetanus toxoid cannot be expected to produce an adequate permanent immunity, a number of investigators have confirmed and extended the observation of Ramon3 to the effect that an organism, once immunized, will respond to further injections of toxoid with an accelerated and increased antitoxin production. That this response to the "injection de rappel" does occur has b...
متن کاملAerosol immunization of guinea pigs with fluid tetanus toxoid.
The concept of mass vaccination of large populations by inhalation of a vaccine in the form of an aerosol [Aleksandrov and Gefen, J. Microbiol. Epidemiol. Immunobiol. (USSR) 31:997, 1960; Sawyer, Kuehne, and Gochenour, Military Med. 129:1040, 1964] has a strong appeal. Aerosol vaccination could immunize a maximal number of people in a minimal period of time, and possibly could confer superior p...
متن کاملImmunogenicity of IRIV- versus alum-adjuvanted diphtheria and tetanus toxoid vaccines in influenza primed mice.
The immunogenicity and protectivity of two different toxoid vaccines were compared in mice. In one formulation, toxoids (diphtheria or tetanus) were adsorbed to alumoxid, whereas in the other formulation the toxoids were crosslinked to immunopotentiating reconstituted influenza virosomes (IRIVs). A preimmunization with influenza antigens is necessary for a good anti-toxoid antibody response whe...
متن کاملThe Purification and Concentration of Diphtheria Toxoid
By precipitation with acetone at 4 degrees C. a refined diphtheria toxoid was obtained as a dry powder, readily soluble in aqueous solutions. The powder itself appears to be stable. When dissolved in half the original volume of physiological salt solution, the toxoid remained stable, in the cold room, for a period of 7 months. Only toxoids should be used which have been completely detoxified by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Public Health and the Nations Health
سال: 1942
ISSN: 0002-9572
DOI: 10.2105/ajph.32.7.690